Cris Ross

Cris Ross is a Venture Partner at Aegis Ventures and the former Chief Information Officer of Mayo Clinic, bringing more than 30 years of leadership across healthcare, technology, and government. At Aegis, he helps surface and evaluate opportunities for new company creation and advises portfolio companies on commercialization, health system integration, and strategic partnerships, drawing on a career spent bridging clinical operations and enterprise technology.

Ross served as Mayo Clinic's CIO for more than a decade before retiring in late 2024, leading the health system's $1.5 billion Epic electronic health record migration, establishing AI partnerships with Google and Microsoft, and expanding virtual care during the pandemic. Earlier, he held CIO roles at CVS Health/MinuteClinic and Optum Behavioral Health and served as EVP for interoperability at Surescripts. He chaired the HIMSS board and has advised HHS, the CDC, and the VA. A two-time cancer survivor, he co-authored Diagnosed: An Insider's Guide for Your Healthcare Journey.