Agenda

date

Thursday, November 5, 2026

LOCATION

555 Convene

Dress

Business Casual

10:00 AM

Welcome to the Aegis Summit

John Beadle

Co-Founder and Managing Partner
Aegis Ventures

Part 1: Mapping the Terrain

10:20 AM

The Forces Reshaping Health

Jason Furman

Aetna Professor of the Practice of Economic Policy
Harvard University

Peter Orszag

CEO and Chairman
Lazard

10:45 AM

Leading through Disruption: What the Best Leaders do Differently

Simon Freakley

Executive Chairman
Alix Partners

Disruption has replaced economic cycles as business's defining challenge, especially in healthcare. Drawing on AlixPartners' seven-year Disruption Index, Simon Freakley shares how leaders navigate AI, tariffs, inflation, geopolitics, and regulation. While CEOs struggle to prioritize, growth leaders treat disruption as a catalyst for action. Simon explores what sets them apart and how healthcare organizations can turn disruption into advantage.

Part 2: Redrawing the Map

11:10 AM

Women's Health: Building the Next Generation of Companies

Chelsea Clinton

Vice Chair
 Clinton Foundation

Kate Ryder

Chief Executive Officer
Maven Clinic

Murray Brozinsky

Partner, Aegis Ventures
Moderator
11:35 AM

From Predictive to Preventive: Technology, Humanity, and the Future of Healthcare

Jamie Metzl

Founder and Chair
OneShared.World

Healthcare is entering a new era. As AI, genomics, biotechnology, and vast health datasets converge, medicine is shifting from reactive treatment to precision, prediction, and prevention. Healthcare futurist Jamie Metzl explores how these
advances are transforming disease detection, drug development, care delivery, and health economics, and what leaders must do to thrive as healthcare focuses on keeping people well.

12:00PM

Lunch

Part 3: The Next Horizon

1:00 PM

What Elite Sport Can Teach Us About Performance

Fin Kirwan

Chief of Olympic and Paralympic Sport
United States Olympic and Paralympic Committee

Geoff Yang

Founding Partner | CEO | Chairman
Redpoint Partners | Apeiron Life | US Olympic and Paralympic Foundation

Olympic races are won by fractions of a second, so every part of an athlete's training, sleep and recovery is measured. Fin Kirwan oversees that work for Team USA as Chief of Olympic and Paralympic Sport. Geoff Yang, Founding Partner of
Redpoint Ventures, now invests in and builds healthspan companies. The discussion will focus on how executives can apply the same science to perform at their best.

1:35 PM

Healthcare 2050: Building What's Next

Amy Abernethy, MD, PhD

Co-Founder
Highlander Health

Patrick Conway, MD

Chief Executive Officer
Optum

Nate Gross, MD

Head of Health
OpenAI

George Yancopoulos, MD, PhD

President & CSO
Regeneron Pharmaceuticals

David Feinberg, MD

Chairman, Oracle Health
Moderator

Imagine healthcare in 2050, rebuilt from the ground up by technologies only beginning to take hold today. Led by Oracle Health Chairman Dr. David Feinberg, this panel brings together leaders who have run research at the FDA, payment innovation at Medicare, and health strategy at OpenAI and Anthropic. The discussion will focus on what that system could look like, and what leaders and investors should back now to make that future real.

2:20 PM

Leading at Scale: The Future of American Healthcare

Stephen Hemsley

Chief Executive Officer
UnitedHealth Group
Dr. John

John Noseworthy, MD

Chairman, Aegis Digital Consortium
Moderator
Transforming an organization at national scale is one of leadership's hardest tests. Few executives know that challenge like Stephen Hemsley, who built Optum during his first run as CEO of UnitedHealth Group (2006 to 2017) and returned to lead the company in 2025. In conversation with former Mayo Clinic CEO Dr. John Noseworthy, he'll share what it takes to lead at that scale, and where he sees American healthcare heading next.
2:45 PM

Coffee & Conversations

Part 4: Charting the Course

3:20 PM

The View from Washington: Policy Levers for Affordability and Access

Abe Sutton

Deputy Administrator, Director
CMS and CMS Innovation Center

Rafid Fadul, MD

Chief Medical Officer/ Acting Deputy Director
ARPA-H

Mark McClellan, MD, PhD

Founding Director, Duke-Margolis Institute for Health Policy
Moderator

Federal policy is among the most powerful forces shaping healthcare affordabilityand access. This panel of Washington insiders will explore how transparency, datasharing and new sites of care can bring costs down at scale, and what it will takefor new technology to reach every patient.

3:55 PM

Financing the Frontier: Where Investors Are Placing Their Bets

Galym Imanbayev, MD

Partner
Lightspeed Venture Partners

Meera Mani, MD, PhD

General Partner
Town Hall Ventures

John Beadle

Managing Partner, Aegis Ventures
Moderator
Healthcare technology is attracting a new wave of capital, and with it, new ideas about what a breakthrough company looks like. Top healthtech investors will reveal where they're deploying capital, the signals they track to spot breakthrough opportunities early, and how they're thinking about value in today's market.
4:30 PM

The Last Word

Ezekiel Emanuel, MD, PhD

Vice Provost for Global Initiatives
University of Pennsylvania

John Driscoll

Venture Partner, Aegis Ventures | Chairman of Waystar
Moderator
4:55 PM

Reflections on the Day

John Beadle

Co-Founder and Managing Partner, Aegis Ventures
Moderator

5:00 PM

Cocktails & Conversation

6:00 PM

Event Ends