Bold ventures, breakthrough results
Aegis Ventures is a NYC-based venture studio that partners with entrepreneurs and industry leaders to build and scale AI-native healthtech companies that tackle the hard problems in healthcare

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The Aegis platform combines deep insights, aligned capital, and proprietary access to customers to substantially increase the velocity and success rate of the new companies we build
Our Growing Portfolio
We’re building AI-powered companies that tackle the hard problems in healthcare. Since inception, we have launched five companies that reimagine how healthcare is delivered, and we’re only just getting started.
Ascertain deploys AI agents to automate workflows, transform operations, and usher in the workforce of the future


Avandra unlocks the value of real-world imaging data to advance medical research, diagnostics, and care


Caregentic empowers every patient with a GenAI companion that serves as a 24/7 extension of their care team


Hume AI develops emotionally intelligent voice AI systems to better understand and respond to human emotional cues with expressive, lifelike speech


Optain combines AI, retinal imaging, and oculomics to enable access to low cost, non-invasive screening for systemic disease


Wavelet is redefining the standard of care in fetal medicine with a non-invasive, AI-powered fetal brain monitoring solution enabling real-time detection of neurological distress







What our Partners say

"Working with Aegis means having a partner who thinks at the system level while moving at startup speed. They provide exceptional end-to-end support, from securing early customers and top-tier talent to raising capital."
"Working with Aegis means having a partner who thinks at the system level while moving at startup speed. They provide exceptional end-to-end support, from securing early customers and top-tier talent to raising capital."

"Participating in the Aegis Digital Consortium has allowed IU Health to partner with like-minded health systems in building and investing in new solutions at scale. Together we are addressing common problems and creating new businesses that will transform health care."
"Participating in the Aegis Digital Consortium has allowed IU Health to partner with like-minded health systems in building and investing in new solutions at scale. Together we are addressing common problems and creating new businesses that will transform health care."

"At Memorial Hermann, we view innovation as a disciplined pathway to solve real operational and clinical problems. The Aegis Digital Consortium has been a valuable forum for pragmatic insight-sharing and peer learning among health systems, helping shape scalable solutions to shared challenges"
"At Memorial Hermann, we view innovation as a disciplined pathway to solve real operational and clinical problems. The Aegis Digital Consortium has been a valuable forum for pragmatic insight-sharing and peer learning among health systems, helping shape scalable solutions to shared challenges"

"We see hundreds of tech solutions in search of a problem every year. Aegis has flipped that script. Being a founding member of their Digital Consortium, we’ve been incredibly impressed by the caliber of their network, management team and the companies they curate. Endeavor Health has a rigorous intake requirement: innovation has to solve real problems. Aegis consistently delivers on that front. In fact, we’re actively adopting, piloting, or co-developing with nearly their entire portfolio right now, and we've swapped out some incumbents for their solutions. It’s exactly the kind of practical, high-impact collaboration we look for."
"We see hundreds of tech solutions in search of a problem every year. Aegis has flipped that script. Being a founding member of their Digital Consortium, we’ve been incredibly impressed by the caliber of their network, management team and the companies they curate. Endeavor Health has a rigorous intake requirement: innovation has to solve real problems. Aegis consistently delivers on that front. In fact, we’re actively adopting, piloting, or co-developing with nearly their entire portfolio right now, and we've swapped out some incumbents for their solutions. It’s exactly the kind of practical, high-impact collaboration we look for."

"Our collaboration with Aegis Ventures has exemplified what's possible when you combine leading clinical, technology, and business resources to advance healthcare innovation. Together we've fast-tracked the creation of cost-effective, validated solutions that solve important challenges across our enterprise and can now be replicated with health systems across the country."
"Our collaboration with Aegis Ventures has exemplified what's possible when you combine leading clinical, technology, and business resources to advance healthcare innovation. Together we've fast-tracked the creation of cost-effective, validated solutions that solve important challenges across our enterprise and can now be replicated with health systems across the country."

"Aegis has been instrumental in expanding our data network by forging partnerships with leading health systems, providing strategic guidance on our business model, and helping us scale initiatives with biopharma and medical researchers to improve and enhance life-saving treatments."
"Aegis has been instrumental in expanding our data network by forging partnerships with leading health systems, providing strategic guidance on our business model, and helping us scale initiatives with biopharma and medical researchers to improve and enhance life-saving treatments."

"UPMC Enterprises’ partnership with the Digital Consortium has been a valuable opportunity to continue building deep relationships with peer health system leaders. Together, we navigate health care challenges and collaborate to develop meaningful solutions and scale innovative companies that advance health care."
"UPMC Enterprises’ partnership with the Digital Consortium has been a valuable opportunity to continue building deep relationships with peer health system leaders. Together, we navigate health care challenges and collaborate to develop meaningful solutions and scale innovative companies that advance health care."

"As they work towards a more sustainable future, health systems can and must play a central role in architecting the next generation of healthtech innovation. I am thrilled to support Aegis as we partner closely with health systems to reimagine the experience of healthcare for patients and caregivers."
"As they work towards a more sustainable future, health systems can and must play a central role in architecting the next generation of healthtech innovation. I am thrilled to support Aegis as we partner closely with health systems to reimagine the experience of healthcare for patients and caregivers."

"What sets Aegis apart is how they think like operators, not just investors. They've been in the trenches with us - from refining our go-to-market strategy to making the introductions that led to our first million in ARR. It's the kind of partnership that actually moves the needle."
"What sets Aegis apart is how they think like operators, not just investors. They've been in the trenches with us - from refining our go-to-market strategy to making the introductions that led to our first million in ARR. It's the kind of partnership that actually moves the needle."

"We have created an enduring partnership of trusted people working together, for the reason they all went into healthcare in the first place — which is to provide better care to patients, families and communities."
"We have created an enduring partnership of trusted people working together, for the reason they all went into healthcare in the first place — which is to provide better care to patients, families and communities."

"Aegis had the conviction to back Hume’s vision from our earliest days and was an incredible partner as we defined our early product and go-to-market strategy. After four years, Aegis remains an integral strategic partner, helping us apply our latest breakthroughs in affective computing and multimodal AI to bring to market AI tools that advance human well-being."
"Aegis had the conviction to back Hume’s vision from our earliest days and was an incredible partner as we defined our early product and go-to-market strategy. After four years, Aegis remains an integral strategic partner, helping us apply our latest breakthroughs in affective computing and multimodal AI to bring to market AI tools that advance human well-being."

"Our partnership with Aegis has been a key success factor in our mission to deliver faster, easier, and more equitable disease screening by accelerating our footprint with leading US health systems and global partners."
"Our partnership with Aegis has been a key success factor in our mission to deliver faster, easier, and more equitable disease screening by accelerating our footprint with leading US health systems and global partners."

"Collaborating with Aegis has given Ascertain access to diverse distribution channels, workflows, and data—resources we believe will unlock new levels of efficiency for healthcare workers to help usher in the healthcare workforce of the future."
"Collaborating with Aegis has given Ascertain access to diverse distribution channels, workflows, and data—resources we believe will unlock new levels of efficiency for healthcare workers to help usher in the healthcare workforce of the future."

"Aegis has created an exceptional talent environment — one that attracts operators, clinicians, and technologists who could thrive anywhere, but choose to build together here. It’s a rare blend of intellectual rigor, humility, and shared purpose that defines how great companies get built."
"Aegis has created an exceptional talent environment — one that attracts operators, clinicians, and technologists who could thrive anywhere, but choose to build together here. It’s a rare blend of intellectual rigor, humility, and shared purpose that defines how great companies get built."
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"Our mission to drive innovative health care transformation forward aligns well with participating in the Aegis Digital Consortium. Through the consortium, we are collaborating with other health systems to develop new solutions to help solve the challenges we're facing as a health care industry. By working together, we can provide better care to patients and families across Ohio and beyond."
"Our mission to drive innovative health care transformation forward aligns well with participating in the Aegis Digital Consortium. Through the consortium, we are collaborating with other health systems to develop new solutions to help solve the challenges we're facing as a health care industry. By working together, we can provide better care to patients and families across Ohio and beyond."


"Aegis brings the ecosystem, experience, and capital needed to accelerate product development, clinical adoption, and commercialization. Together, we have a real opportunity to redefine what ‘standard of care’ means in fetal medicine - and to save lives."
"Aegis brings the ecosystem, experience, and capital needed to accelerate product development, clinical adoption, and commercialization. Together, we have a real opportunity to redefine what ‘standard of care’ means in fetal medicine - and to save lives."
Our Values
Aegis is an unparalleled environment with exceptional people from interdisciplinary backgrounds working to transform healthcare.
We listen first and learn from those closest to how healthcare is delivered and administered
We believe progress moves at the speed of trust, and we invest in long-tenured relationships
We advance technology with integrity and build solutions that drive real-world change
We tackle the hard problems with an eye towards system-wide solutions that truly move the needle
We believe in the power of small teams united by shared purpose to drive major systemic change
We pursue ambitious outcomes with urgency and resilience, upholding high standards of excellence


