Bold ventures, breakthrough results
Aegis Ventures is a NYC-based venture studio that partners with entrepreneurs and health systems to launch and scale meaningful healthtech startups that drive healthcare forward
Unlock the value of real world data to improve care
Real-world data
Reimagining how patients access and engage with healthcare
Patient Experience
Reimagining how patients access and engage with healthcare
Patient Experience
Redesigned workflows to get patients home more quickly
Automating Workflows
Novel biomarkers to transform disease detection and monitoring
Creating New Biomarkers
The Aegis platform combines deep insights, aligned capital, and proprietary access to customers to increase the velocity and success of new company creation
05
Portfolio Companies Launched to Date
80%
Seed to Series A Conversion
$200M+
Capital Raised by Portfolio Companies
25
Strategic Partners/Co-Investors
Our Growing Portfolio
We’re building AI-powered companies that tackle the hard problems in healthcare. Since inception, we have launched five companies that reimagine how healthcare is delivered, and we’re only just getting started.
Automating Workflows
Ascertain
Ascertain deploys AI agents to automate workflows, transform operations, and to usher in the workforce of the future.
Unlocking Real-World Data
Avandra
Avandra unlocks the value of real-world imaging data to advance medical research, diagnostics, and care.
Reimagining Consumer Experience
Caregentic
Caregentic empowers every patient with a GenAI companion as a 24/7 extension of their care team.
Reimagining Consumer Experience
Hume
Hume builds empathetic AI systems that measure and optimize for human emotional wellbeing.
Creating New Biomarkers
Optain
Optain combines AI, retinal imaging, and oculomics to enable access to low cost, non-invasive screening for systemic disease.
What our Partners say
Working with Aegis means having a partner who thinks at the system level while moving at startup speed. They provide exceptional end-to-end support, from securing early customers and top-tier talent to raising capital.
Ash Zenooz, MD
Venture Partner at Aegis, Board Chair at Caregentic
Working with Aegis means having a partner who thinks at the system level while moving at startup speed. They provide exceptional end-to-end support, from securing early customers and top-tier talent to raising capital.
Ash Zenooz, MD
Venture Partner at Aegis, Board Chair at Caregentic
Participating in the Aegis Digital Consortium has allowed IU Health to partner with like-minded health systems in building and investing in new solutions at scale. Together we are addressing common problems and creating new businesses that will transform health care.
Nicole Paulk
Chief Strategy Officer, Indiana University Health
Participating in the Aegis Digital Consortium has allowed IU Health to partner with like-minded health systems in building and investing in new solutions at scale. Together we are addressing common problems and creating new businesses that will transform health care.
Nicole Paulk
Chief Strategy Officer, Indiana University Health
At Memorial Hermann, we view innovation as a disciplined pathway to solve real operational and clinical problems—not just to experiment, but to scale what works in how healthcare is accessed, delivered, and experienced. The Aegis Digital Consortium has been a valuable forum for pragmatic insight-sharing and peer learning among health systems, helping shape scalable solutions to shared challenges
Feby Abraham
EVP, Chief Strategy and Innovations Officer at Memorial Hermann Health System
At Memorial Hermann, we view innovation as a disciplined pathway to solve real operational and clinical problems—not just to experiment, but to scale what works in how healthcare is accessed, delivered, and experienced. The Aegis Digital Consortium has been a valuable forum for pragmatic insight-sharing and peer learning among health systems, helping shape scalable solutions to shared challenges
Feby Abraham
EVP, Chief Strategy and Innovations Officer at Memorial Hermann Health System
Our collaboration with Aegis Ventures has exemplified what's possible when you combine leading clinical, technology, and business resources to advance healthcare innovation. Together we've fast-tracked the creation of cost-effective, validated solutions that solve important challenges across our enterprise and can now be replicated with health systems across the country.
Michael Dowling
CEO and President of Northwell Health
Our collaboration with Aegis Ventures has exemplified what's possible when you combine leading clinical, technology, and business resources to advance healthcare innovation. Together we've fast-tracked the creation of cost-effective, validated solutions that solve important challenges across our enterprise and can now be replicated with health systems across the country.
Michael Dowling
CEO and President of Northwell Health
Aegis has been instrumental in expanding our data network by forging partnerships with leading health systems, providing strategic guidance on our business model, and helping us scale initiatives with biopharma and medical researchers to improve and enhance life-saving treatments.
Ryan Tarzy
CEO and Founder of Avandra
Aegis has been instrumental in expanding our data network by forging partnerships with leading health systems, providing strategic guidance on our business model, and helping us scale initiatives with biopharma and medical researchers to improve and enhance life-saving treatments.
Ryan Tarzy
CEO and Founder of Avandra
UPMC Enterprises’ partnership with the Digital Consortium has been a valuable opportunity to continue building deep relationships with peer health system leaders. Together, we navigate health care challenges and collaborate to develop meaningful solutions and scale innovative companies that advance health care.
Brent Burns
Executive Vice President, UPMC Enterprises
UPMC Enterprises’ partnership with the Digital Consortium has been a valuable opportunity to continue building deep relationships with peer health system leaders. Together, we navigate health care challenges and collaborate to develop meaningful solutions and scale innovative companies that advance health care.
Brent Burns
Executive Vice President, UPMC Enterprises
As they work towards a more sustainable future, health systems can and must play a central role in architecting the next generation of healthtech innovation. I am thrilled to support Aegis as we partner closely with health systems to reimagine the experience of healthcare for patients and caregivers.
David Feinberg, MD
Executive Chairman at Aegis Ventures
As they work towards a more sustainable future, health systems can and must play a central role in architecting the next generation of healthtech innovation. I am thrilled to support Aegis as we partner closely with health systems to reimagine the experience of healthcare for patients and caregivers.
David Feinberg, MD
Executive Chairman at Aegis Ventures
What sets Aegis apart is how they think like operators, not just investors. They've been in the trenches with us - from refining our go-to-market strategy to making the introductions that led to our first million in ARR. It's the kind of partnership that actually moves the needle.
Russ Johannesson
CEO of Caregentic
What sets Aegis apart is how they think like operators, not just investors. They've been in the trenches with us - from refining our go-to-market strategy to making the introductions that led to our first million in ARR. It's the kind of partnership that actually moves the needle.
Russ Johannesson
CEO of Caregentic
We have created an enduring partnership of trusted people working together, for the reason they all went into healthcare in the first place — which is to provide better care to patients, families and communities.
John Noseworthy, MD
Chairman of the Aegis Digital Consortium
We have created an enduring partnership of trusted people working together, for the reason they all went into healthcare in the first place — which is to provide better care to patients, families and communities.
John Noseworthy, MD
Chairman of the Aegis Digital Consortium
Aegis had the conviction to back Hume’s vision from our earliest days and was an incredible partner as we defined our early product and go-to-market strategy. After four years, Aegis remains an integral strategic partner, helping us apply our latest breakthroughs in affective computing and multimodal AI to bring to market AI tools that advance human well-being.
Alan Cowen, PhD
CEO & Chief Scientist of Hume
Aegis had the conviction to back Hume’s vision from our earliest days and was an incredible partner as we defined our early product and go-to-market strategy. After four years, Aegis remains an integral strategic partner, helping us apply our latest breakthroughs in affective computing and multimodal AI to bring to market AI tools that advance human well-being.
Alan Cowen, PhD
CEO & Chief Scientist of Hume
Our partnership with Aegis has been a key success factor in our mission to deliver faster, easier, and more equitable disease screening by accelerating our footprint with leading US health systems and global partners.
Jeff Dunkel
CEO of Optain Health
Our partnership with Aegis has been a key success factor in our mission to deliver faster, easier, and more equitable disease screening by accelerating our footprint with leading US health systems and global partners.
Jeff Dunkel
CEO of Optain Health
Collaborating with Aegis has given Ascertain access to diverse distribution channels, workflows, and data—resources we believe will unlock new levels of efficiency for healthcare workers to help usher in the healthcare workforce of the future.
Mark Michalski, MD
CEO of Ascertain
Collaborating with Aegis has given Ascertain access to diverse distribution channels, workflows, and data—resources we believe will unlock new levels of efficiency for healthcare workers to help usher in the healthcare workforce of the future.
Mark Michalski, MD
CEO of Ascertain
Aegis has created an exceptional talent environment — one that attracts operators, clinicians, and technologists who could thrive anywhere, but choose to build together here. It’s a rare blend of intellectual rigor, humility, and shared purpose that defines how great companies get built.
Clinton Browning
Partner, ECB Star Group
Aegis has created an exceptional talent environment — one that attracts operators, clinicians, and technologists who could thrive anywhere, but choose to build together here. It’s a rare blend of intellectual rigor, humility, and shared purpose that defines how great companies get built.
Clinton Browning
Partner, ECB Star Group
Our Values
Aegis is an unparalleled environment with exceptional people from interdisciplinary backgrounds working to transform healthcare.
Lead with humility
We listen first and learn from those closest to the doctor-patient relationship.
Build trust to move fast
We believe progress moves at the speed of trust, and we invest in long-tenured relationships.
Innovate responsibly
We advance technology with integrity and build solutions that create real-world change.
Take big swings
We tackle healthcare’s hardest problems, pursuing opportunities that drive impact.
Be nimble and scrappy
We believe in the power of small teams united by shared purpose to drive major systemic change.
Execute relentlessly
We pursue ambitious outcomes with urgency and hold ourselves accountable.
