Combining the Best of Two Worlds

Healthcare operates under the principle of "first, do no harm." Silicon Valley prefers to "move fast and break things."

We harmonize these philosophies by respecting the practice of medicine while applying cutting edge technology to drive breakthrough outcomes

If you want to go far, go together

The future of healthcare won’t be built in isolation. At Aegis, we partner with industry leaders to ideate and launch purpose-built companies that solve their greatest challenges.

Our History

Aegis was founded in 2021 to build transformative healthtech companies in close partnership with leaders across the healthcare ecosystem. Since then, we’ve launched five companies that that reimagine how healthcare is delivered. Partnerships are in our DNA, and we created the Aegis Digital Consortium to scale the next generation of game changing companies.


With this foundation in place, we’ve proven the model and are now focused on expanding our impact.

Story Timeline
Story Timeline
2021-2023

Creating the Blueprint

Initial partnership with Northwell Health. Launched four companies, creating a blueprint for company creation alongside strategic partners.

2024

Expanding our Healthcare Ecosystem

Expansion of  our partnership model through the Aegis Digital Consortium of 11 leading health systems to scale our impact across the ecosystem.

2025

Building a Scaled Company-Creation Platform

Scaling current portfolio companies to major impact and launching the next set of groundbreaking companies.

We believe that health systems must play a central role in architecting the next generation of healthtech innovation

US Map showing 11 leading health systems across the U.S to develop and scale AI-enable technology solutions to address healthcare’s most pressing challenges

The Aegis Digital Consortium

In partnership with 11 leading regional health systems, we are building an ecosystem of companies that address core clinical and operational pain points.

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Our Company Creation Strategy

To date, Aegis has co-founded five companies with leading health systems and entrepreneurs across five core investment themes.

Automating Workflows

Driving efficiency, quality, and scale by redesigning core healthcare workflows with AI.
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Ascertain

Creating New Biomarkers

Transforming disease detection and monitoring with AI and novel biomarkers.
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Optain

Reimagining Consumer Experience

Reimagining how patients access, navigate, and engage with healthcare.
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Caregentic
Hume

Unlocking Real-World Data

Accelerating drug development and optimizing treatments with real-world data.
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Avandra

Expanding Share of Care

Redesigning fragmented care delivery into seamless, coordinated models that drive better outcomes and lower costs.
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The Aegis Advantage

We believe the next generation of healthcare companies will require both scale and craft. Our model combines the reach of a scaled platform investor with the discipline of a hands-on builder.

Scaled platform
  • Combine capital with hands-on company building
  • Gain differentiated insights through partnerships
  • Leverage ecosystem to drive early adoption
Craftsman-like model
  • Prioritize quality over quantity
  • Forge close founder partnerships
  • Build conviction-driven companies with long-term focus
The Aegis Advantage
  • 01
    Create proprietary deals across stages
  • 02
    Attract capital, distribution, and talent
  • 03
    Build disciplined, high-impact companies positioned for durable success

Creating the next generation of health tech companies demands a new approach

As the cost of software approaches zero and capital becomes a commodity, the next generation of value will be built on trust, access, and alignmentnot code and capital alone.

Traditional VC-backed companies
The next generation of companies
The moat
Code was hard to write
Trust is hard to earn
The builder profile
Outsider hacking healthcare
Embedded operator reimagining it
The path to scale
Build big to move fast
Build lean to move smart
The venture model
Management fees as business model
Realized value as business model

Built on experience and purpose, the Aegis model is our blueprint for sustainable healthtech innovation

Our portfolio