Combining the Best of Two Worlds

Healthcare operates under the principle of "first, do no harm." Silicon Valley prefers to "move fast and break things."

We harmonize these philosophies by respecting the practice of medicine when applying cutting edge technology to drive breakthrough outcomes

Partnerships are
in our DNA

The future of healthcare will be built through trust-based partnerships. At Aegis, we collaborate with industry leaders to ideate and launch purpose-built companies that solve their greatest challenges.

Our History

Aegis was founded in 2021 to build transformative healthtech companies in close partnership with industry leaders. Since then, we’ve launched five companies that reimagine how healthcare is innovated and delivered. We launched the Aegis Digital Consortium to scale a new paradigm for building game-changing companies.


With our model now proven and ready for scale, we're expanding our reach and impact across the healthcare ecosystem.

Story Timeline
Story Timeline
2021-2023

Creating the Blueprint

Initial partnership with Northwell Health. Launched four companies, creating a blueprint for company creation alongside strategic partners

2024

Expanding our Healthcare Ecosystem

Expansion of our partnership model through the Aegis Digital Consortium of 11 leading health systems to scale our impact across the ecosystem

2025

Building a Scaled Company-Creation Platform

Scaling current portfolio companies to major impact and launching the next set of groundbreaking companies

We believe that health systems must play a central role in architecting the next generation of healthtech innovation

US Map showing 11 leading health systems across the U.S to develop and scale AI-enable technology solutions to address healthcare’s most pressing challenges

The Aegis Digital Consortium

In partnership with 11 leading regional health systems, we are building an ecosystem of companies that address core clinical and operational pain points.

Learn more

Our Company Creation Strategy

To date, Aegis has co-founded five companies with leading health systems and entrepreneurs across five core investment theses.

Automating Workflows

Improving efficiency and quality by redesigning healthcare workflows with AI
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Ascertain

Creating New Biomarkers

Transforming disease detection and monitoring with AI and novel biomarkers
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Optain

Reimagining Consumer Experiences

Reimagining how patients access, navigate, and engage with healthcare
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Caregentic
Hume

Unlocking Real-World Data

Accelerating drug development and optimizing treatments with real-world data
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Avandra

Expanding Share of Care

Building innovative care models that drive continuity across the patient journey
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Creating the next generation of health tech companies demands a new approach

As the cost of software approaches zero and capital becomes a commodity, the next generation of value will be built on trust, access, and alignmentnot code and capital alone.

Traditional VC-backed companies
The Aegis Model for next generation companies
The moat
Code was hard to write
Trust is hard to earn
The builder profile
Outsider hacking healthcare
Embedded operator reimagining it
The path to scale
Build big to move fast
Build lean to move smart
The venture model
Management fees as business model
Realized value as business model

The Aegis Advantage

We believe the next generation of healthcare companies will require both scale and craft. Our model combines the reach of a scaled platform investor with the discipline of a hands-on builder.

Scaled platform
  • Combine capital with hands-on company building
  • Gain differentiated insights through partnerships
  • Leverage ecosystem to drive early adoption
Craftsman-like model
  • Prioritize quality over quantity
  • Forge close founder partnerships
  • Build conviction-driven companies with long-term focus
The Aegis Advantage
  • 01
    Create proprietary deals across stages
  • 02
    Attract capital, distribution, and talent
  • 03
    Build disciplined, high-impact companies positioned for durable success

We have created a reproducible blueprint for healthtech innovation

Our portfolio